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1.
Rev. peru. med. exp. salud publica ; 35(4): 695-698, oct.-dic. 2018. graf
Article in Spanish | LILACS | ID: biblio-985786

ABSTRACT

RESUMEN La tuberculosis en el lactante es un cuadro de difícil diagnóstico por las pruebas diagnósticas que muchas veces resultan negativas y por la dificultad de identificar la fuente de transmisión. Se presenta el caso de un lactante varón de un mes de vida que presenta irritabilidad, taquipnea, fiebre, pobre ganancia de peso desde el nacimiento y hepatomegalia, además, tiene el antecedente materno de tuberculosis pre-extensivamente resistente a drogas y reacción granulomatosa tuberculoide con tinción auramina positiva para bacilos ácido-alcohol resistentes en la histopatología de placenta. Ante la sospecha de tuberculosis congénita, es referido al Instituto Nacional de Salud del Niño para estudio diagnóstico y tratamiento; el paciente presenta una evolución clínica favorable y sin reacciones adversas al tratamiento. El diagnóstico de tuberculosis congénita debe considerarse en lactantes con signos clínicos sugestivos de la enfermedad y mantener la sospecha ante la presencia del antecedente materno de infección por Mycobacterium tuberculosis.


ABSTRACT Tuberculosis in infants is a clinical case difficult to diagnose by regular testing which often yield negative results; additionally, the source of transmission is difficult to identify. This work presents the case of a one-month old nursing boy presenting irritability, tachypnea, fever, poor gain weight from birth, and hepatomegaly. Additionally, he had the maternal history of pre-extensively drug- resistant tuberculosis and tuberculoid granulomatosis reaction with positive auramine tincture for acid-alcohol resistant bacilli at histopathology of the placenta. With a suspected congenital tuberculosis, he was referred to the National Children's Health Institute for diagnosis and treatment. The patient showed a favorable clinical evolution and no adverse reactions to treatment. The diagnosis of congenital tuberculosis must be considered in infants with suggestive clinical signs of the disease and such suspicion must be maintained with the presence of a maternal history of Mycobacterium tuberculosis infection.


Subject(s)
Adult , Female , Humans , Infant, Newborn , Male , Pregnancy , Pregnancy Complications, Infectious/microbiology , Infectious Disease Transmission, Vertical , Extensively Drug-Resistant Tuberculosis/congenital , Extensively Drug-Resistant Tuberculosis/transmission , Extensively Drug-Resistant Tuberculosis/diagnosis , Extensively Drug-Resistant Tuberculosis/drug therapy
2.
Rev. peru. med. exp. salud publica ; 26(3): 380-386, jul.-sept. 2009. graf, ilus, mapas
Article in Spanish | LILACS, LIPECS | ID: lil-564044

ABSTRACT

En este artículo se describe el estado actual de las epidemias de tuberculosis multidrogo resitente (TB MDR) y tuberculosis extensivamente resistente a drogas (TB XDR) en el Perú. Se realiza un análisis de nuestra situación con respecto al resto de Latinoamérica, y de la distribución temporo espacial de los casos de TB XDR en Lima. También presentamos nuestra reflexión de lo que está pasando y debe cambiar; lo que se resume en darle la importancia debida a un problema que nos está rebasando y anteponer a nuestros propios intereses, los intereses de la humanidad; por consiguiente no podemos callar, y debemos declarar a la tuberculosis como emergencia sanitaria nacional. Eso constituye una respuesta, esperamos, aún viable para el Perú.


In this paper we describe the current situation of the epidemic of multidrug-resistant tuberculosis (TB MDR) andextensively-drug resistant tuberculosis (TB XDR) in Peru. We do an analysis of our situation in comparison with the restof Latin America, and of the temporal spatial distribution of the TB XDR cases in Lima, We also present our reflectionabout what is happening and we believe it must change, as summarized in giving due weight to a problem that is comingover andwe should put before own interests, the interests of humanity, therefore we cannot keep silent, and we must declare TB as a national health emergency. That is an answer, hopefully, still viable for Peru.


Subject(s)
Humans , Poverty , Public Health , Tuberculosis, Multidrug-Resistant , Tuberculosis, Multidrug-Resistant/epidemiology , Tuberculosis, Multidrug-Resistant/prevention & control , Peru
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